Phosphatase Modulators

Phosphatase Modulators Phosphatase Modulators Driving further the research on mammalian alkaline phosphatase structure and function, P...

Phosphatase Modulators

Phosphatase Modulators
Phosphatase Modulators
Driving further the research on mammalian alkaline phosphatase structure and function, Phosphatase Modulators collects expert contributions into one “how to” manual for basic scientists interested in initiating a drug discovery effort.

While this book contains the traditional method chapters and some typical reviews on the structure and known functions of phosphatases, other contributions are meant to discuss approaches and alternatives useful in making “go/no-go” decisions in high throughput screening (HTS) and lead optimization campaigns. Many chapters focus on tissue-nonspecific alkaline phosphatase (TNAP) as well as protein phosphatases. Written for the highly successful Methods in Molecular Biology series, chapters in this volume include the kind of detail and key implementation advice that promotes reproducible results. Step-by-step and practical, Phosphatase Modulators offers a path to understanding many of the facets and complexities associated with undertaking a drug discovery effort and will serve as a roadmap to initiating those efforts.

Table of contents Phosphatase Modulators:

Front Matter....Pages i-x
Back Matter....Pages 1-6
....Pages 7-25
Methods in Molecular Biology 1053

Michael R. Jackson (auth.), José Luis Millán (eds.)
Phosphatase Modulators

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