Drug Development: Principles, Methodology and Emerging Challenges

Drug Development: Principles, Methodology and Emerging Challenges Drug Development: Principles, Methodology and Emerging Challenges In...

Drug Development: Principles, Methodology and Emerging Challenges

Drug Development: Principles, Methodology and Emerging Challenges

In this book, the authors discuss the principles, methodology and emerging challenges of drug development.

Topics include outsourcing and technology transfer in pharmaceutical companies; analytical tools and chemometrics in the drug development process; the use of cytometry for drug development of cell cycling inhibitors; and the antiproliferative effects of phenolic compounds isolated from the Brazilian propolis.

Table of contents - Drug Development: Principles, Methodology and Emerging Challenges:

Chapter 1 - Outsourcing and Technology Transfer (pp. 1-34)
Authors / Editors: (Dave Elder, Glaxo Smith Kline R&D, Hertfordshire, United Kingdom)
Chapter 2 - Analytical Tools and Chemometrics in Drug Development Process: A Review (pp.35-62)
Authors / Editors: (D. Melucci, C. Locatelli, M. Locatelli, Department of Chemistry “Giacomo Ciamician”, University of Bologna, Bologna, Italy, and others)
Chapter 3 - Use of Flow Cytometry for Drug Development of Cell Cycle Inhibitor: The Example of Edotecarin, a Topoisomerase I Inhibitor (pp. 63-88)
Authors / Editors: (Paolo Cappella, Veronica Patton, Clara Albanese, Rachele Alzani, Roberta Ceruti, Marina Ciomei, Drug Discovery Oncology, Nerviano Medical Sciences srl, Nerviano, Italy)
Chapter 4 - Antiproliferative Effects of Phenolic Compounds Isolated from Brazilian Propolis (pp. 89-98)
Authors / Editors: (Soon-Chang Cho, Min-Jae Lee, Hong De Xu, Sang-Seop Han, Yun Lyul Lee, Seung-Wan Lee, Dae-Hun Park, Center for Senior Industry, Yeongdong, Chungbuk-do, Korea, and others)

Marco Rossi, Santina Bertone
Drug Development: Principles, Methodology and Emerging Challenges